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The role of long-lived plasma cells in autoimmunity
Sergio Arce1, Giuliana Cassese, Anja Hauser
1German Rheumatism Research Center, Berlin, Germany. arce@drfz.de
Immunobiology
|February 28, 2003
Abstract:
Recent results on the biology of plasma cells have shown that these cells can survive as long as memory B cells. Possibly, such long-lived plasma cells are also involved in the production of autoantibodies. Here, we discuss the potential involvement of long-lived plasma cells in the pathogenesis of autoimmune disease and the consequences it has for the development of effective therapeutic strategies.