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Landau-Kleffner Syndrome: Localization of Epileptogenic Lesion Using Wavelet- Cross-Correlation Analysis
Yuko Mizuno-Matsumoto1, Toshiki Yoshimine, Yasuo Nii
1Department of Human Welfare and Department of Child Education, Osaka Jonan Women's University, Osaka, Japan
Epilepsy & Behavior : E&B
|March 1, 2003
Abstract:
Magnetoencephalographic findings in a 6-year-old patient suffering from acquired aphasia with convulsive disorder (Landau-Kleffner Syndrome, LKS) are presented. The data were analyzed using wavelet-cross-correlation analysis, a nonstationary analysis method developed to analyze the localization of an epileptogenic lesion and the propagation of epileptiform discharges. The results indicate that LKS might be a disorder of the primary temporal cortex, and that the auditory neural network may function as the circuit for the epileptic discharge propagation.