Rietveld refinement on x-ray diffraction patterns of bioapatite in human fetal bones
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Updated: Sep 16, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Carlo Meneghini1, Maria Chiara Dalconi, Stefania Nuzzo
1Istituto Nazionale per la Fisica della Materia (INFM), University of Roma Tre, Italy. meneghini@fis.uniroma3.it
Abstract:
Bioapatite, the main constituent of mineralized tissue in mammalian bones, is a calcium-phosphate-based mineral that is similar in structure and composition to hydroxyapatite. In this work, the crystallographic structure of bioapatite in human fetuses was investigated by synchrotron radiation x-ray diffraction (XRD) and microdiffraction ( micro -XRD) techniques. Rietveld refinement analyses of XRD and micro -XRD data allow for quantitative probing of the structural modifications of bioapatite as functions of the mineralization process and gestational age.
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