Plasma cell granuloma of the thyroid with Hashimoto's thyroiditis: report of a rare case
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Updated: Sep 27, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Kimberly Mugler1, Loretta Gaido, John Ryder
1Department of Pathology, University of Colorado Health Sciences Center, Denver, CO 80262, USA.
Abstract:
As only eight cases have been previously reported in the literature, plasma cell granuloma of the thyroid gland is a rare entity. This condition can be confused with a benign or malignant neoplastic thyroid process. In this article, we describe a new case of plasma cell granuloma of the thyroid gland that occurred in a 46-year-old man who also had Hashimoto's thyroiditis. This case represents only the second documented instance of a plasma cell granuloma of the thyroid occurring in the setting of Hashimoto's thyroiditis. Moreover, it is only the second case of a plasma cell granuloma that has been reported in a male.
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