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Related Experiment Videos

Protein family annotation in a multiple alignment viewer.

Jason M Johnson1, Keith Mason, Ciamac Moallemi

  • 1Pfizer Discovery Technology Center, 620 Memorial Drive, Cambridge, MA 02139, USA. jason_johnson@merck.com

Bioinformatics (Oxford, England)
|March 4, 2003
PubMed
Summary

Pfaat is a Java-based tool for protein family analysis, offering multiple sequence alignment editing and viewing. It integrates structural data and user annotations for comprehensive protein family exploration.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Structural Biology

Background:

  • Protein family analysis is crucial for understanding protein function and evolution.
  • Existing tools may lack integrated features for comprehensive analysis.

Purpose of the Study:

  • To introduce the Pfaat protein family alignment annotation tool.
  • To provide a versatile platform for protein family analysis.

Main Methods:

  • Developed as a Java-based application.
  • Incorporates multiple sequence alignment editing and viewing functionalities.
  • Integrates dendrograms, secondary and tertiary protein structure visualization, and SRS retrieval.

Main Results:

  • The tool offers extensive user-annotation capabilities.

Related Experiment Videos

  • Enables subgroup comparison within protein families.
  • Provides a merged display of structural and alignment data.

    • Conclusions:

    • Pfaat is a comprehensive tool for protein family analysis.
    • Its integrated features facilitate detailed investigation of protein families.
    • The tool enhances the understanding of protein relationships and structures.