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Severe Raynaud's phenomenon with chronic hepatis C disease treated with interferon
Raffaele Iorio1, Maria Immacolata Spagnuolo, Angela Sepe
1Department of Pediatrics, University of Naples Federico II, Italy. riorio@unina.it
The Pediatric Infectious Disease Journal
|March 5, 2003
Abstract:
Severe Raynaud's phenomenon developed in a 5-year-old girl with chronic hepatitis C infection at the fifth month of interferon therapy in the absence of cryoglobulinemia and other conditions commonly associated with secondary Raynaud's phenomenon. Although interferon therapy was promptly discontinued, Raynaud's phenomenon persisted for 4 months with appearance of necrotic-ulcerous lesions at the tips of fingers.