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Capofungin therapy for Aspergillus lung infection in a boy with chronic granulomatous disease
Svea Sallmann1, Antje Heilmann, Frank Heinke
1Department of Pediatrics, University of Dresden, Germany.
The Pediatric Infectious Disease Journal
|March 5, 2003
Abstract:
Neutrophils of patients with chronic granulomatous disease (CGD) are profoundly defective in killing microorganisms. As in patients with chemotherapy-induced neutropenia, CGD patients are highly susceptible to life-threatening invasive Aspergillus infections, and conventional antimycotic treatment is not always successful. The new drug, caspofungin, was used to treat Aspergillus lung infection in one child with CGD.