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Peripheral keratitis associated with erythema elevatum diutinum
Anthony J Aldave1, Judy L Shih, Sayed Jovkar
1Department of Ophthalmology, University of California, San Francisco/Francis I Proctor Foundation, San Francisco, California, USA. aldave@jsei.ucla.edu
American Journal of Ophthalmology
|March 5, 2003
Summary
Erythema elevatum diutinum (EED), a rare vasculitis, can cause peripheral keratitis. Dapsone effectively treated both skin and eye inflammation in this case report.
Area of Science:
- Ophthalmology
- Dermatology
- Rheumatology
Background:
- Erythema elevatum diutinum (EED) is an uncommon immune-complex-mediated vasculitis primarily affecting the skin.
- Ocular manifestations of EED are rare, but peripheral keratitis can occur.
Observation:
- A 25-year-old male with a known diagnosis of EED presented with inflammatory peripheral keratitis in his left eye.
- Systemic workup for other causes of vasculitic peripheral ulcerative keratitis was negative.
Findings:
- The patient's sclerokeratitis was considered an ocular manifestation of his underlying cutaneous EED.
- Initiation of dapsone therapy led to a rapid and positive response in both the cutaneous lesions and ocular inflammation.
Implications:
- This case highlights the importance of considering EED in the differential diagnosis of vasculitic peripheral keratitis.
- Early recognition and treatment of ocular involvement in EED can prevent vision loss.