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Related Experiment Videos

Polymers in contact with the body.

R N King, D J Lyman

    Environmental Health Perspectives
    |June 1, 1975
    PubMed
    Summary

    The clinical use of medical polymers is growing, necessitating research into their biological interactions. This study reviews polymer properties, host effects, and material stability for safe clinical application.

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    Area of Science:

    • Biomaterials Science
    • Polymer Chemistry
    • Medical Device Research

    Background:

    • Clinical applications of polymeric materials for tissue repair and organ restoration are rapidly increasing.
    • This rise necessitates comprehensive research into medically used polymers and their biological interactions.

    Purpose of the Study:

    • To provide historical and current information on clinical polymer use.
    • To establish a basis for assessing polymer acceptability in biological systems.
    • To discuss the essential properties of polymers used in medical applications.

    Main Methods:

    • Review of historical and current clinical applications of polymers.
    • Discussion of polymer properties from the perspective of host-material interactions.
    • Analysis of factors influencing polymer stability in vivo.

    Main Results:

    • Polymers must demonstrate specific properties for safe clinical use.
    • Assessment involves considering the material's effect on the host and the host's effect on the material.
    • Factors like synthesis, processing, sterilization, and degradation impact polymer performance.

    Conclusions:

    • Understanding host-material interactions is crucial for evaluating medical polymers.
    • Polymer stability is influenced by numerous factors throughout its lifecycle.
    • Poly(ethylene terephthalate) serves as an example for discussing these complex considerations.

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