Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cosmetic applications for solid lipid nanoparticles (SLN).

Sylvia A Wissing1, Rainer H Müller

  • 1Institut für Pharmazie, Pharmazeutische Technologie, Biopharmazie und Biotechnologie, Freie Universität Berlin, Kelchstrasse 31, D-12169 Berlin, Germany.

International Journal of Pharmaceutics
|March 5, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sub-50 nm ultra-small organic drug nanosuspension prepared by cavi-precipitation and its brain targeting potential.

International journal of pharmaceutics·2021
Same author

Can the cavi-precipitation process be exploited to generate smaller size drug nanocrystal?

Drug development and industrial pharmacy·2021
Same author

Formulation development of lipid nanoparticles: Improved lipid screening and development of tacrolimus loaded nanostructured lipid carriers (NLC).

International journal of pharmaceutics·2019
Same author

BergaCare SmartLipids: commercial lipophilic active concentrates for improved performance of dermal products.

Beilstein journal of nanotechnology·2019
Same author

Dermal smartPearls - Optimized silica particles for commercial products & mechanistic considerations.

International journal of pharmaceutics·2019
Same author

Nanoporous smartPearls for dermal application - Identification of optimal silica types and a scalable production process as prerequisites for marketed products.

Beilstein journal of nanotechnology·2019

Solid lipid nanoparticles (SLN) enhance skin hydration and improve sunscreen efficacy. These novel delivery systems offer significant advantages for cosmetic applications, reducing active ingredient needs.

Area of Science:

  • Cosmetic Science
  • Nanotechnology
  • Dermatology

Background:

  • Solid lipid nanoparticles (SLN) are advanced delivery systems.
  • SLN offer benefits for pharmaceutical and cosmetic active ingredients.

Purpose of the Study:

  • Highlight advantages of SLN for cosmetic applications.
  • Investigate SLN for skin hydration, occlusive effects, and sunscreen formulations.

Main Methods:

  • In vitro analysis of SLN particle size and film formation for occlusive effects.
  • In vivo study evaluating SLN in an oil-in-water cream for skin hydration.
  • Assessment of SLN as physical sunscreens and carriers for molecular sunscreens.

Main Results:

  • In vitro data demonstrated particle size dependency of SLN's occlusive effect.

Related Experiment Videos

  • In vivo study showed 4% SLN increased skin hydration by 31% after 4 weeks.
  • SLN enabled a 50% reduction in molecular sunscreen concentration without compromising protection.

    • Conclusions:

    • SLN provide significant benefits for cosmetic applications, including enhanced skin hydration.
    • SLN particle size influences their occlusive properties.
    • SLN are effective as physical sunscreens and carriers, optimizing sunscreen formulations.