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Dextrans in microsurgery: A review.
1Department of Plastic and Recostructive Surgery, Addenbrooke's Hospital, Cambridge, United Kingdom. navidjallali@hotmail.com
Microsurgery
|March 5, 2003
Summary
Dextrans are reviewed for free tissue transfer, but they cannot replace sound surgical methods. Caution is advised, particularly for elderly patients receiving dextran treatments.
Area of Science:
- Microsurgery
- Vascular Surgery
- Pharmacology
Background:
- Free tissue transfer is a complex reconstructive surgery.
- Dextrans are plasma volume expanders with historical use in vascular surgery.
- Optimizing outcomes in free tissue transfer remains a clinical challenge.
Purpose of the Study:
- To review the current applications of dextrans in free tissue transfer.
- To discuss recommended regimens, indications, and potential complications associated with dextran use.
- To evaluate the role of dextrans as an adjunct to surgical technique.
Main Methods:
- Literature review of studies on dextran use in free tissue transfer.
- Analysis of recommended dextran administration protocols.
- Discussion of reported complications and adverse events.
Main Results:
- Dextrans are discussed concerning their efficacy and safety in free tissue transfer.
- Current guidelines and clinical indications for dextran use are presented.
- Complications, including potential risks in specific patient populations, are highlighted.
Conclusions:
- Dextrans should not be considered a substitute for meticulous surgical technique in free tissue transfer.
- Cautious utilization of dextrans is recommended, especially in elderly patients.
- The role of dextrans as an adjunct therapy requires careful consideration of risks and benefits.