Related Experiment Videos
[Early recurrent meningioma with malignant transformation: case report]
Hiroki Nakatsuka1, Shiro Ohue, Shinsuke Ohta
1Department of Neurological Surgery, Ehime University School of Medicine, Japan.
No Shinkei Geka. Neurological Surgery
|March 6, 2003
Summary
Malignant transformation of meningioma is uncommon, but this case shows a rare recurrence with malignant change just 4 months post-surgery. This highlights the potential for residual tumor cells to undergo malignant transformation and recur.
Area of Science:
- Neuro-oncology
- Surgical Pathology
Background:
- Meningiomas are typically benign tumors of the meninges.
- Malignant transformation of meningioma occurs in 10-38% of cases.
- Recurrence with malignant transformation shortly after surgery is rare.
Observation:
- A 64-year-old female presented with a right parietal convexity meningioma.
- Initial surgery revealed a psammomatous meningioma with a transitional meningioma-like area; no malignancy was detected.
- Four months post-surgery, the patient developed left-sided hemiparesis and numbness, indicating recurrence.
Findings:
- Imaging revealed a recurrent cystic tumor with ring enhancement.
- Histological re-examination confirmed malignant transformation of the meningioma.
- The patient died due to tumor recurrence within a year.
Implications:
- This case suggests that residual tumor cells with malignant potential may remain after initial resection.
- Postoperative malignant transformation of these cells can lead to rapid recurrence.
- Further research into early detection and prevention of malignant transformation in meningioma is warranted.