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New chemical syntheses of cholest-4,6-dien-3-one
Edward J Parish1, Hang Sun, Ding Lu
1Department of Chemistry, Auburn University, Alabama 36849-5312, USA. parisej@auburn.edu
Lipids
|March 6, 2003
Abstract:
Steroidal dienones represent a significant class of compounds that are useful intermediates in the further functionalization of the steroid nucleus. Their chemical synthesis can be problematic owing to the lack of a simplified method of preparation and the occurrence of impurities that can be difficult to remove. We have endeavored to develop new methods of chemical synthesis of cholest-4,6-dien-3-one that would yield a product of high purity.