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Updated: Jul 16, 2026

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Clinical predictors of leak after laparoscopic Roux-en-Y gastric bypass for morbid obesity
E C Hamilton1, T L Sims, T T Hamilton
1Clinical Center for the Surgical Management of Obesity and the Southwestern Center for Minimally Invasive Surgery, University of Texas Southwestern Medical Center, Dallas, 75390, USA.
Background:
Gastrointestinal leak is a complication of laparoscopic Roux-en-Y gastric bypass (LRYGB). Contrast studies may underdiagnose leaks, forcing surgeons to rely solely on clinical data. This study was designed to evaluate various clinical signs for detecting leakage after LRYGB.
Methods:
We retrospectively reviewed 210 consecutive patients who underwent LRYGB between April 1999 and September 2001. There were nine documented leaks (4.3%). Clinical signs between patients with leaks (group 1) and those without leaks (group 2) were compared using univariate and multivariate logistic regression analysis.
Results:
Evidence of respiratory distress and a heart rate exceeding 120 beats per min were the two most sensitive indicators of gastrointestinal leak. Routine upper gastrointestinal contrast imaging detected only two of nine leaks (22%).
Conclusion:
Leak after LRYGB may be difficult to detect. Evidence of respiratory distress and tachycardia exceeding 120 beats per min may be the most useful clinical indicators of leak after laparoscopic Roux-en-Y gastric bypass.

