Combined endovascular/neurosurgical therapy of blister-like distal internal carotid aneurysms
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Updated: Aug 7, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
D M Pelz1, G G Ferguson, S P Lownie
1Department of Diagnostic Radiology and Nuclear Medicine, London Health Sciences Centre, University Campus, University of Western Ontario, London, Ontario, Canada.
Objective:
To describe a novel therapeutic strategy for the treatment of "blister-like" aneurysms of the distal internal carotid artery (ICA). Direct surgical treatments of these fragile lesions have been associated with generally poor outcomes.
Methods:
Two consecutive patients presenting with acute subarachnoid hemorrhage from "blister-like" aneurysms were treated with preliminary balloon occlusion of the ICA, followed by surgical trapping of the ICA beyond the aneurysm.
Results:
The treatment resulted in complete thrombosis of both aneurysms with no clinical complications.
Conclusion:
This combined endovascular-neurosurgical approach offers a controlled, safer alternative to primary surgical therapy of "blister-like" aneurysms.
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