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Updated: Sep 27, 2026

RNAi-mediated Control of Aflatoxins in Peanut: Method to Analyze Mycotoxin Production and Transgene Expression in the Peanut/Aspergillus Pathosystem
09:44

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Published on: December 21, 2015

Potential for dietary protection against the effects of aflatoxins in animals

Allen K Bingham1, Timothy D Phillips, John E Bauer

  • 1Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843-4474, USA.

Journal of the American Veterinary Medical Association
|March 7, 2003
PubMed
Abstract

No abstract available in PubMed .

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...