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Dihydroisocoumarins and a tetralone from Cytospora eucalypticola
Tetsuo Kokubun1, Nigel C Veitch, Paul D Bridge
1Royal Botanic Gardens, Kew, Richmond, Surrey, TW9 3AB, UK. t.kokubun@kew.org.uk
Phytochemistry
|March 7, 2003
Abstract:
Two dihydroisocoumarins, 3,5-dimethyl-8-hydroxy-7-methoxy-3,4-dihydroisocoumarin and 3,5-dimethyl-8-methoxy-3,4-dihydroisocoumarin were isolated from a culture filtrate of Cytospora eucalypticola, together with three known dihydroisocoumarins and a tetralone derivative. Their structures were determined by spectroscopic methods. These isocoumarins are mildly antifungal, and antibacterial towards gram positive bacteria. A known compound, 5-hydroxymethylmellein, showed mild antifeedant activity towards Spodoptera littoralis.