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Antifungal diterpenes from Hypoestes serpens (Acanthaceae)
Lalao Rasoamiaranjanahary1, Andrew Marston, David Guilet
1Institut de Pharmacognosie et Phytochimie, Université de Lausanne, CH-1015 Lausanne, Switzerland.
Phytochemistry
|March 7, 2003
Abstract:
Two new diterpenes, fusicoserpenol A and dolabeserpenoic acid A, with antifungal activity, were isolated from leaves of Hypoestes serpens (Acanthaceae). Their structures were elucidated by means of spectrometric methods including 1D and 2D NMR experiments and MS analysis. X-ray crystallographic analysis confirmed the structure of fusicoserpenol A and established the relative configuration.