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Intradermal Inoculation of Mycobacterium avium in the Mouse Ear
Published on: July 3, 2025
Intestinal nematodes and pulmonary tuberculosis
Ricardo Tristão-Sá1, Rodrigo Ribeiro-Rodrigues, Luciléia T Johnson
1Universidade Federal do Espírito Santo, Vitória, ES, Brazil.
Abstract:
We report a significantly higher prevalence of intestinal nematodes in patients with pulmonary tuberculosis (TB) compared to a matched control group: 33/57 (57.8%) in patients with TB and 18/86 (20.9%) in the control group; OR = 5.19; 95% CI = 2.33-11.69; p = 0.000). When TB patients eosinophilia was also significantly higher among those with intestinal parasites (69.8%) compared to those without this condition (45.6%). We hypothesized that the immune modulation induced by nematodes is a factor that enhances TB infection/progression and that eosinophilia seen in TB patients is a consequence of helminth infection.
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