Related Experiment Videos
[Acute therapy of ischemic stroke]
Wilfried Lang1, Wolfgang Lalouschek
1Neurologische Abteilung, Krankenhaus der Barmherzigen Brüder Wien, Grosse Mohrengasse 9, A-1021 Wien. wilfried.lang@univie.ac.at
Wiener Medizinische Wochenschrift (1946)
|March 8, 2003
Summary
High-dose heparin increased hemorrhage risk in stroke patients, but not in those with TIA or minor stroke. Stroke complications, like pneumonia, often occur early and impact long-term outcomes.
Area of Science:
- Neurology
- Internal Medicine
- Critical Care Medicine
Context:
- Stroke management in Vienna neurological departments.
- Analysis of complications and risk factors post-stroke.
Purpose:
- To identify risk factors for secondary hemorrhage and poor functional outcomes in stroke patients.
- To highlight the importance of complication management in stroke units.
Summary:
- Thrombolysis was administered to 3.7% of admitted stroke patients.
- High-dose heparin correlated with increased secondary symptomatic hemorrhage risk (OR 10.3), though not observed in TIA or minor stroke patients.
- A diastolic blood pressure decrease >20 mmHg tripled the risk of adverse outcomes.
- Pneumonia emerged as an independent risk factor for poor functional outcomes at three months.
- Stroke complications are most common within the first five days.
Impact:
- Informs clinical practice regarding heparin use and blood pressure management in stroke care.
- Emphasizes the critical role of stroke units in preventing and managing early complications.
- Highlights pneumonia as a significant predictor of long-term disability after stroke.