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Plasmid DNA electrotransfer: a new non viral method for gene therapy in oncology
1UMR 7001 CNRS-ENSCP / Aventis, CRVA 13 quai Jules Guesde 94403, Vitry sur Seine, France.
Technology in Cancer Research & Treatment
|March 8, 2003
Abstract:
With some defined conditions, electric pulses delivery to tissue in vivo can greatly enhance DNA transfection. We here describe the application in oncology of intratumoral or intramuscular DNA electrotransfer by using muscle as a secretory tissue of transgenic proteins displaying anticancer properties.