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[Emergency lung transplantation].

V Calvo1, J Padilla, A García-Zarza

  • 1Servicio de Cirugía Torácica y Grupo de Trasplante Pulmonar de Valencia. Hospital Universitario La Fe. Valencia. España. vjcalvo@comv.es

Archivos De Bronconeumologia
|March 8, 2003
PubMed
Summary
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Emergency lung transplants (C-0) can be effective and efficient, despite higher perioperative risk. Long-term survival in C-0 patients is comparable to scheduled transplants when adequately monitored, challenging traditional views on transplant efficiency.

Area of Science:

  • Thoracic Surgery
  • Transplantation Medicine
  • Critical Care Medicine

Background:

  • Lung donor scarcity necessitates efficient resource allocation in lung transplantation.
  • Emergency lung transplants (C-0) are often avoided due to perceived poor outcomes.
  • Spain permits C-0 lung transplants for listed patients, contrasting with international practices.

Purpose of the Study:

  • To evaluate and compare the outcomes of scheduled versus emergency (C-0) lung transplants.
  • To assess the efficiency and effectiveness of C-0 lung transplantation.
  • To analyze factors influencing perioperative mortality and long-term survival in lung transplant recipients.

Main Methods:

  • A retrospective study of lung transplant recipients from 1992-2001.

Related Experiment Videos

  • Survival analysis using Kaplan-Meier, Cox regression, and chi-squared tests.
  • Comparison of perioperative mortality and long-term outcomes between C-0 and scheduled procedures, considering variables like age, sex, and transplant type.

    • Main Results:

    • Of 183 lung transplants, 11 were C-0 and 172 were scheduled.
    • Perioperative mortality was significantly higher for C-0 (36.4%) versus scheduled (8.7%) transplants (p=0.0035).
    • Despite higher perioperative risk, 5-year survival rates were similar (58.16% scheduled vs. 57.14% C-0), indicating comparable long-term outcomes.

    Conclusions:

    • Lung transplantation is an effective and efficient procedure for C-0 patients.
    • Adequate patient monitoring is crucial for successful C-0 lung transplantation.
    • Findings support the viability of C-0 lung transplantation, challenging its exclusion based solely on perioperative risk.