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Infectious keratitis after LASIK.

Carol L Karp1, Sonal S Tuli, Sonia H Yoo

  • 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida.

Ophthalmology
|March 8, 2003
PubMed
Summary
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Infectious keratitis after laser-assisted in situ keratomileusis (LASIK) can threaten vision, with symptom onset varying by organism. Atypical microbes present diagnostic and treatment challenges.

Area of Science:

  • Ophthalmology
  • Microbiology
  • Surgical Complications

Background:

  • Laser-assisted in situ keratomileusis (LASIK) is a common refractive surgery.
  • Infectious keratitis is a rare but serious complication following LASIK.

Observation:

  • This study reviewed 15 eyes of 13 patients who developed culture-proven infectious keratitis post-LASIK.
  • Infection onset ranged from 1 to 450 days post-surgery.
  • Bacterial keratitis typically presented earlier than mycobacterial, fungal, or acanthamoeba infections.

Findings:

  • Atypical organisms (mycobacteria, fungi, acanthamoeba) led to delayed diagnosis and prolonged disease course.
  • Interface location of infection complicated culturing and topical antibiotic penetration.
  • Management involved topical antibiotics, with some cases requiring flap lifting, amputation, or further surgery.

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Implications:

  • Early identification and appropriate treatment are crucial for managing post-LASIK infectious keratitis.
  • Atypical organisms pose significant diagnostic and therapeutic challenges.
  • Understanding organism-specific timelines aids in timely intervention to preserve vision.