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Adrenocortical response to marathon running.

S T Newmark, T Himathongkam, R P Martin

    The Journal of Clinical Endocrinology and Metabolism
    |February 1, 1976
    PubMed
    Summary
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    Marathon running significantly elevates plasma cortisol and plasma aldosterone levels in highly conditioned male athletes. This study shows the adrenal cortex responds to the intense physical exertion of endurance events.

    Area of Science:

    • Endocrinology
    • Exercise Physiology
    • Sports Medicine

    Background:

    • The adrenal cortex plays a crucial role in the body's response to stress.
    • Endurance exercise, such as marathon running, represents a significant physiological stressor.

    Purpose of the Study:

    • To investigate the response of the adrenal cortex to the physical exertion of marathon running.
    • To measure changes in plasma cortisol and aldosterone levels following a marathon.

    Main Methods:

    • Blood samples were collected from 7 highly conditioned male subjects before and immediately after completing a marathon.
    • Plasma levels of cortisol and aldosterone were quantified.

    Main Results:

    • Both plasma cortisol and plasma aldosterone levels showed a significant increase post-marathon.

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  • These findings indicate a notable adrenal cortex response to prolonged muscular exertion.

    • Conclusions:

    • Marathon running induces a significant endocrine response, characterized by elevated cortisol and aldosterone.
    • The adrenal cortex is activated by the physiological stress of endurance events.