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Recycling and reuse of a polymer-supported scavenger for amine sequestration
Meritxell Guinó1, Emilie Brulé, Yolanda R de Miguel
1Department of Chemistry, King's College London, Strand, London U.K. WC2R 2LS.
Abstract:
The regeneration and reuse of a supported scavenger 1 for amine sequestration has been achieved up to three times without significant loss of activity. The scavenging process between the aldehyde resin 1 and a range of amines has been investigated in detail to determine the scope of this scavenger. Its application for the rapid purification of a small library of secondary amines 7a-j has also been demonstrated, and it has been shown that the large excess of scavenger resin used can be recovered and recycled, making this a more cost-effective process.
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