Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Coumarin therapy in thrombosis.

Graham Pineo1, Russell D Hull

  • 1Foothills Hospital, 601 South Tower, 1403-29 Street, NW, Calgary, Alberta T29 2T9, Canada. pineo@ucalgary.ca

Hematology/Oncology Clinics of North America
|March 12, 2003
PubMed
Summary

Oral anticoagulants, like warfarin, are crucial for preventing and treating blood clots. Their use is increasing for various conditions, including heart attack prevention and post-surgery recovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

External validation of the ADA score for predicting thrombosis among acutely ill hospitalized medical patients from the APEX Trial.

Journal of thrombosis and thrombolysis·2022
Same author

Inverse relationship between body mass index and risk of venous thromboembolism among medically ill hospitalized patients: Observations from the APEX trial.

Thrombosis research·2022
Same author

Machine learning to predict venous thrombosis in acutely ill medical patients.

Research and practice in thrombosis and haemostasis·2020
Same author

Estimation of Acutely Ill Medical Patients at Venous Thromboembolism Risk Eligible for Extended Thromboprophylaxis Using APEX Criteria in US Hospitals.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2019
Same author

Net-clinical benefit of extended prophylaxis of venous thromboembolism with betrixaban in medically ill patients aged 80 or more.

Journal of thrombosis and haemostasis : JTH·2019
Same author

The IMPROVEDD VTE Risk Score: Incorporation of D-Dimer into the IMPROVE Score to Improve Venous Thromboembolism Risk Stratification.

TH open : companion journal to thrombosis and haemostasis·2019

Area of Science:

  • Pharmacology
  • Cardiovascular Medicine
  • Hematology

Background:

  • Oral anticoagulants are primary agents for long-term prophylaxis and treatment of thrombotic disorders.
  • Increasing indications, including myocardial infarction prevention and atrial fibrillation management, are driving rising use.
  • Commonly prescribed in North America for venous thromboembolism prophylaxis after orthopedic surgery.

Purpose of the Study:

  • To review the pharmacology of warfarin sodium.
  • To discuss practical aspects of warfarin use in managing thrombotic disorders.

Main Methods:

  • Literature review of warfarin pharmacology.
  • Discussion of clinical application in thrombotic disorder management.

Main Results:

  • Warfarin sodium is the most utilized oral anticoagulant in North America.
  • The article provides a comprehensive overview of its pharmacological properties.
  • Practical considerations for its clinical use are detailed.

Conclusions:

  • Warfarin remains a cornerstone in managing arterial and venous thrombotic disorders.
  • Understanding its pharmacology and practical use is essential for effective patient care.
  • Its expanding indications underscore its importance in modern medicine.

Related Experiment Videos