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Related Concept Videos

  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Twenty-year Survival After Coronary Artery Surgery: An Institutional Perspective From Emory University.
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Twenty-year Survival After Coronary Artery Surgery: An Institutional Perspective From Emory University.

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Twenty-year survival after coronary artery surgery: an institutional perspective from Emory University.

William S Weintraub1, Stephen D Clements, L Van-Thomas Crisco

  • 1Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Ga, USA. wweintr@emory.edu

Circulation
|March 12, 2003

View abstract on PubMed

Summary
This summary is machine-generated.

Long-term survival after coronary artery bypass graft (CABG) surgery is influenced by various clinical factors. Identifying these mortality correlates can help predict outcomes for patients with coronary atherosclerotic heart disease.

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Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Public Health

Background:

  • Coronary artery bypass graft (CABG) surgery is a common procedure for symptomatic coronary atherosclerotic heart disease.
  • Long-term survival post-CABG and its relationship with mortality predictors remain areas of uncertainty.

Purpose of the Study:

  • To investigate 20-year outcomes after CABG.
  • To identify clinical factors associated with long-term mortality following CABG surgery.

Main Methods:

  • A cohort of 3939 patients undergoing CABG between 1973 and 1979 was analyzed.
  • Outcomes assessed at 20 years included survival, freedom from myocardial infarction, and freedom from repeat CABG.
  • Multivariate analysis was used to identify correlates of late mortality.

Main Results:

  • Twenty-year survival was 35.6%. Key mortality correlates included older age, female sex, hypertension, higher angina class, prior CABG, lower ejection fraction, more diseased vessels, and higher weight.
  • Survival rates varied significantly by age at surgery, with younger patients having better outcomes.
  • Hypertension and female sex were associated with reduced 20-year survival.

Conclusions:

  • Coronary atherosclerotic heart disease requiring CABG is a progressive condition with ongoing risks.
  • Clinical factors significantly influence long-term survival after CABG, aiding in the identification of patients who may benefit most from the procedure.