Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple sclerosis amongst Chinese in Taiwan.

T P Hung, D Landsborough, M S Hsi

    Journal of the Neurological Sciences
    |April 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Persistence of detectable insecticidal proteins from Bacillus thuringiensis (Cry) and toxicity after adsorption on contrasting soils.

    Environmental pollution (Barking, Essex : 1987)·2015
    Same author

    Ascariasis causing acute intestinal obstruction.

    British medical journal·2010
    Same author

    Ascariasis Causing Acute Intestinal Obstruction.

    British medical journal·2010
    Same author

    Observations on plague meningitis.

    British medical journal·2010
    Same author

    [Community-based cervical cancer screening in seven townships in Taiwan].

    Journal of the Formosan Medical Association = Taiwan yi zhi·1995
    Same author

    [Intracranial aneurysm in Taiwan].

    Journal of the Formosan Medical Association = Taiwan yi zhi·1995
    Same journal

    Distinguishing drug-target effects from natural lipid variation and incorporating imaging outcomes in Mendelian randomisation studies of multiple sclerosis.

    Journal of the neurological sciences·2026
    Same journal

    Long-term social cognitive impairment after ischemic stroke: Frequency and association with lesion volume and location in an exploratory pilot study.

    Journal of the neurological sciences·2026
    Same journal

    Subjective cognitive decline among U.S. Cancer survivors, 2017-2024: Prevalence, cancer-specific patterns, and associated factors.

    Journal of the neurological sciences·2026
    Same journal

    Comment on "Comparative impact of mental and cardiovascular comorbidities on adverse outcomes in people with MS".

    Journal of the neurological sciences·2026
    Same journal

    Comment on "Efficacy and safety of conventional immunosuppressant therapies in elderly patients with Neuromyelitis optica spectrum disorder: A target trial emulation study".

    Journal of the neurological sciences·2026
    Same journal

    Increasing incidence of varicella-zoster virus meningitis in Japan, 2011-2022.

    Journal of the neurological sciences·2026
    See all related articles

    Multiple sclerosis (MS) exists in Taiwan, affecting females more often with earlier onset and frequent optic nerve involvement. Atypical MS cases may be more common in Oriental populations.

    Area of Science:

    • Neurology
    • Epidemiology
    • Immunology

    Background:

    • Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system.
    • Its prevalence and clinical characteristics can vary significantly across different ethnic and geographic populations.
    • Understanding MS in non-Western populations is crucial for a comprehensive global perspective.

    Purpose of the Study:

    • To report on the clinical characteristics and prevalence of multiple sclerosis (MS) among the Chinese population in Taiwan.
    • To investigate demographic and clinical features, including disease onset, symptom patterns, and disease severity.
    • To compare findings with Western MS populations and discuss potential atypical presentations in Oriental patients.

    Main Methods:

    • Retrospective analysis of 25 clinically diagnosed multiple sclerosis (MS) cases collected over 20 years in Taiwan.

    Related Experiment Videos

  • Inclusion of 2 autopsy cases for pathological confirmation.
  • Clinical data review including demographics, onset, symptoms, disease course, and cerebrospinal fluid (CSF) analysis.

    • Main Results:

    • Multiple sclerosis (MS) is present in Taiwan, with an estimated prevalence of 0.8/100,000 in northern Taiwan.
    • A significant female preponderance (F:M = 3.2:1) was observed, with earlier disease onset in females.
    • Optic nerve involvement was most frequent at onset and throughout the disease course. Malignant forms and painful tonic spasms were more common in females. Atypical MS presentations were noted.
    • Autopsy cases revealed severe demyelination in the optic nerve and spinal cord.

    Conclusions:

    • Multiple sclerosis (MS) occurs in the Chinese population of Taiwan, though it is relatively uncommon.
    • Clinical presentation in Taiwan shows a female predominance, earlier onset in females, and frequent optic nerve and spinal cord involvement.
    • Atypical MS presentations, potentially differing from Western cases, may be more prevalent in Oriental and tropical regions.