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Updated: Sep 24, 2026

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Management of urinary extravasation in 18 boys with posterior urethral valves
K K Patil1, D T Wilcox, M Samuel
1Department of Paediatric Urology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.
Insights
Urinary extravasation in boys with posterior urethral valves often impairs kidney function. A proposed management algorithm addresses this condition, improving outcomes.
Area of Science:
- Pediatric Urology
- Nephrology
- Radiology
Background:
- Urinary extravasation associated with posterior urethral valves is a rare condition.
- Existing literature is primarily limited to case reports.
Purpose of the Study:
- To propose a management algorithm for urinary extravasation in boys with posterior urethral valves.
- To analyze the clinical presentation, diagnostic imaging, and renal function in affected boys.
Main Methods:
- Retrospective review of 18 boys with posterior urethral valves and urinary extravasation.
- Analysis of clinical features, voiding cystourethrogram, and (99m)technetium mercaptoacetyltriglycine scans.
- Assessment of glomerular filtration rate (GFR) for renal function evaluation.
Main Results:
- Common presentations include abdominal distention and flank mass.
- Boys with ascites showed significantly lower GFR compared to those with ascites and urinoma.
- Impaired renal function was noted in the ipsilateral kidney in unilateral urinoma cases.
Conclusions:
- Renal function is compromised on the side of the urinoma.
- Most patients experience impaired global renal function.
- A novel management algorithm is proposed based on study findings.
Purpose:
Urinary extravasation with associated posterior urethral valves is uncommon and published articles are restricted to case reports. We propose a management algorithm on the basis of presentation of 18 boys with this condition.
Materials And Methods:
In this retrospective review we analyze the clinical features, diagnostic radiological imaging (voiding cystourethrogram and (99m)technetium mercaptoacetyltriglycine scan) and measured glomerular filtration rate (GFR) for assessment of renal function in boys presenting with posterior urethral valves and urinary extravasation. Indications for surgical intervention and long-term outcome were evaluated. Results are presented as mean +/- SD.
Results:
Patient age at presentation was 4 days (range 1 to 28). Salient features at presentation were abdominal distention in 55.5% of cases, flank mass in 55.5%, respiratory distress in 16.6% and septicemia in 22.2%. Patients were categorized into group 1 with ascites (6 boys) and group 2 without ascites (12). Followup was 70.8 +/- 5.6 months. In group 1 the 3 boys with ascites alone had a followup GFR of 29 versus 74 ml. per minute per 1.73 m.2 in 3 with urinoma plus ascites (p = 0.001) at 64 +/- 4.9 months. In group 2 the GFR in 3 boys with bilateral urinoma was 104.7 +/- 30.4 versus 54.3 +/- 29.4 ml. per minute per 1.73 m.2 in the other 9 with unilateral urinoma (p = 0.001) at 36 +/- 4.2 and 81.3 +/- 4.7 months, respectively. The ipsilateral kidney showed reduced function in 6 of 12 boys with unilateral urinoma from both groups.
Conclusions:
Renal function on the side of the urinoma is impaired, and the majority of patients have impaired global renal function. A management algorithm is proposed.
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