Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Pseudomalignant changes in benign phyllodes breast tumor].

J Koren1

  • 1Oddelenie patológie NsP, Zvolen.

Ceskoslovenska Patologie
|March 13, 2003
PubMed
Summary

Unusual breast lesions, benign phylloides tumors with adenosis, can mimic cancer on frozen sections. Immunohistochemistry is crucial for accurate diagnosis of these fibroepithelial breast tumors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The spectrum of indications for ultralong-term EEG monitoring.

Seizure·2024
Same author

Outcome of elderly patients with classical Hodgkin's lymphoma.

Leukemia research·2020
Same author

Emergence of extended-spectrum β-lactamase (ESBL) and/or carbapenemase producing Enterobacteriaceae (CPE) and their antimicrobial resistance.

Bratislavske lekarske listy·2019
Same author

Automatic multimodal detection for long-term seizure documentation in epilepsy.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2017
Same author

Reduced electrode arrays for the automated detection of rhythmic and periodic patterns in the intensive care unit: Frequently tried, frequently failed?

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2017
Same author

Applicability of NeuroTrend as a bedside monitor in the neuro ICU.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2017

Area of Science:

  • Pathology and Oncology
  • Breast Lesion Diagnosis

Background:

  • Phylloides tumors of the breast are fibroepithelial neoplasms with varying biological potential, categorized as benign, borderline, or malignant.
  • Breast adenoses encompass benign lesions characterized by glandular proliferation, with several subtypes including florid and sclerosing adenosis.

Observation:

  • This study presents two rare cases of benign phylloides tumors in middle-aged women.
  • These tumors exhibited significant modification by various adenosis types and intense myoepithelial proliferation.
  • The complex histology presented diagnostic challenges, particularly mimicking invasive ductal or lobular carcinoma on frozen section analysis.

Findings:

  • Benign phylloides tumors co-occurring with adenosis can present complex histological features.
  • Intensive myoepithelial proliferation further complicates the differentiation from malignant breast cancers.
  • Immunohistochemical methods are essential for definitive diagnosis.

Implications:

  • Accurate differentiation of these benign but complex breast lesions is critical to avoid misdiagnosis as invasive cancer.
  • The findings highlight the importance of advanced diagnostic techniques, such as immunohistochemistry, in breast pathology.
  • Enhanced understanding of these rare tumor variants can improve patient management and treatment strategies.

Related Experiment Videos