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New approaches to reversal of neuromuscular block
Anton Bom1, John K Clark, Ronald Palin
1Organon Laboratories Ltd, Departments of Pharmacology and Medicinal Chemistry, Newhouse, ML1 5SH, Scotland, UK.
Current Opinion in Drug Discovery & Development
|March 13, 2003
Abstract:
Although numerous reversal agents for neuromuscular block (NMB) have been known for some time, investigations on new approaches were initiated only recently. The different approaches used in an attempt to avoid the muscarinic side effects associated with the antagonists of NMB that are currently available are reviewed.