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Updated: Aug 17, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
Chronic myeloid leukaemia at the Kenyatta National Hospital, Nairobi
N A Othieno-Abinya1, L O Nyabola, G W Kiarie
1Department of Medicine, Faculty of Medicine, College of Health Sciences, University of Nairobi, PO Box 19676, Nairobi, Kenya.
Objective:
To determine the clinical and haematological factors associated with treatment and outcome of chronic myeloid leukaemia (CML) at Kenyatta National Hospital.
Design:
Retrospective survey of patients treated for chronic myeloid leukaemia.
Setting:
Kenyatta National hospital, Nairobi, Kenya, between April 1990 and August 2000.
Subjects:
Patients with chronic myeloid leukaemia.
Results:
One hundred and four patients, 55 males and 49 females, age range 10-72 years with a median age of 35 years. Treatment with busulphan getting less popular in favour of hydroxyurea. Median follow-up 20 months with none of the clinical and haematological parameters impacting significantly on duration of follow-up.
Conclusion:
CML occurs at a younger age-group in Kenya, and none of the clinical or haematological parameters appears to impact on follow-up duration.
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