The combinatorial synthesis of bicyclic privileged structures or privileged substructures

Pharmacology and macrophage modulation of HPGDS inhibitor PK007 demonstrate reduced disease severity in DMD-affected muscles of the mdx mouse model.

Skeletal muscle·2025

Dual therapy with corticosteroid ablates the beneficial effect of DP2 antagonism in chronic experimental asthma.

Nature communications·2024

Prostaglandins in the Inflamed Central Nervous System: Potential Therapeutic Targets.

Current drug targets·2024

Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD mdx Model Mice.

Life (Basel, Switzerland)·2021

PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production.

Science translational medicine·2018

Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23.

BMC bioinformatics·2016

Conformational Switching on Lipid Interfaces: Lessons from Refolding and Membrane Insertion of Diphtheria Toxin, BCL-2 Apoptotic Regulators and pHLIP.

Chemical reviews·2026

Folding and Oligomerization of CLC Channels and Transporters.

Chemical reviews·2026

Materials and Device Engineering for Efficient, Stable, and Scalable Monolithic Perovskite/Silicon Tandem Photovoltaics.

Chemical reviews·2026

Conditional Transmembrane Peptides as Allosteric Modulators: Thermodynamic and Functional Perspectives in Membrane Protein Regulation.

Chemical reviews·2026

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Chemical reviews·2026

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Chemical reviews·2026

Two undescribed bisabolane-type sesquiterpenoids from the endophytic fungus Penicillium herquei.

Journal of Asian natural products research·2026

In Vitro Effects of Centaurea ovina (Roudbari Cornflower) Aqueous and Ethanolic Extracts on Staphylococcus saprophyticus: Growth Inhibition, Antibiofilm Activity, and Reduced ureC/uafA Transcripts.

International journal of microbiology·2026

Sperm-disrupting activity of a root bark fraction of Flueggea virosa (Roxb. ex willd.) royle uncovered using LC-MS/MS profiling and functional evaluation.

Frontiers in pharmacology·2026

The relevance of cannabinoid receptor 2 in the central nervous system: an update over the last 3 years.

Frontiers in behavioral neuroscience·2026

Do sigma-1 receptor agonists offer therapeutic promise for Alzheimer's disease?

Expert opinion on pharmacotherapy·2026

Protective Effects of Geraniol in Rheumatoid Arthritis Through Attenuation of Inflammation and Oxidative Stress.

Endocrine, metabolic & immune disorders drug targets·2026

Related Experiment Videos

The combinatorial synthesis of bicyclic privileged structures or privileged substructures

Related Concept Videos

Pharmacology and macrophage modulation of HPGDS inhibitor PK007 demonstrate reduced disease severity in DMD-affected muscles of the mdx mouse model.

Dual therapy with corticosteroid ablates the beneficial effect of DP2 antagonism in chronic experimental asthma.

Prostaglandins in the Inflamed Central Nervous System: Potential Therapeutic Targets.

Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD <i>mdx</i> Model Mice.

PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-<b>λ</b> production.

Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23.

Conformational Switching on Lipid Interfaces: Lessons from Refolding and Membrane Insertion of Diphtheria Toxin, BCL-2 Apoptotic Regulators and pHLIP.

Folding and Oligomerization of CLC Channels and Transporters.

Materials and Device Engineering for Efficient, Stable, and Scalable Monolithic Perovskite/Silicon Tandem Photovoltaics.

Conditional Transmembrane Peptides as Allosteric Modulators: Thermodynamic and Functional Perspectives in Membrane Protein Regulation.

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Two undescribed bisabolane-type sesquiterpenoids from the endophytic fungus <i>Penicillium herquei</i>.

In Vitro Effects of <i>Centaurea ovina</i> (Roudbari Cornflower) Aqueous and Ethanolic Extracts on <i>Staphylococcus saprophyticus</i>: Growth Inhibition, Antibiofilm Activity, and Reduced <i>ureC</i>/<i>uafA</i> Transcripts.

Sperm-disrupting activity of a root bark fraction of <i>Flueggea virosa</i> (Roxb. ex willd.) royle uncovered using LC-MS/MS profiling and functional evaluation.

The relevance of cannabinoid receptor 2 in the central nervous system: an update over the last 3 years.

Do sigma-1 receptor agonists offer therapeutic promise for Alzheimer's disease?

Protective Effects of Geraniol in Rheumatoid Arthritis Through Attenuation of Inflammation and Oxidative Stress.

Related Experiment Videos

The combinatorial synthesis of bicyclic privileged structures or privileged substructures

Related Concept Videos

Related Articles