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Ultrastructural localization of Ani s 1, a major allergen from the fish parasite Anisakis simplex
F Gómez-Aguado1, A Picazo, M L Caballero
1Department of Pathology, Carlos III Hospital, Sinesio Delgado 10, 28029 Madrid, Spain. fgomez.hciii@madrid.salud.org
Parasitology Research
|March 13, 2003
Abstract:
No data about the nature or function of the first major Anisakis simplex allergen, named Ani s 1, is available. The aim of this study was to investigate the ultrastructural localization of this protein, to obtain further information about it. Ani s 1 was detected in secretory granules of the excretory gland and occasionally lining the main excretory canal. Our results suggest that Ani s 1 could be a secretory product and could have an enzymatic function related to mechanisms of infection.