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Updated: Sep 27, 2026

Extraction of Short-chain Fatty Acids from Mouse Feces Using A Two-phase Acid–Solvent Method
Published on: July 17, 2026
Simple and efficient solid support scavenging of excess acyl donors after enzymatic acylations in organic solvents
Alexander Ya Usyatinsky1, Nadezhda M Astakhova, Yuri L Khmelnitsky
1Albany Molecular Research Inc., 21 Corporate Circle, P.O. Box 15098, Albany, New York 12212, USA.
Abstract:
A simple and efficient method for removing excess acyl donors following enzymatic acylations in organic solvents was developed. This method is based on selective chemical scavenging of acyl donors using an amino-functionalized solid support, and does not affect the desired acylated product. A wide variety of different acyl donors, including vinyl and trifluoroethyl esters and vinyl carbonates, can be quantitatively removed by this method, thus providing a simple and highly efficient tool for purification of reaction products after enzymatic acylation.
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