[A novel whole blood aggregometer]

Ruriko Konishi1, Norimasa Seo

  • 1Department of Anesthesiology, Jichi Medical School, Tochigi 329-0498.

Masui. the Japanese Journal of Anesthesiology
|March 14, 2003
PubMed

We examined ADP-induced platelet aggregability in 45 patients by novel whole blood aggregometer based on the screen filtration pressure method. Platelet aggregation could be easily and immediately checked without preparing platelet rich plasma. This aggregometer was useful for determination of anesthetic methods for a patient with an anti-platelet therapy. However, PATI (platelet aggregately threshold index) demonstrated the lowest value 5 minutes after blood collection and the valve was stabilized at higher level for 30 to 120 minutes. Time-dependent change should be considered for assessment of platelet aggregability in a clinical study.