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[Psoriasis and cardio-vascular disorders].

Anna Wojas-Pelc1, Lidia Rajzer, Marek Rajzer

  • 1Katedra i Klinika Dermatologii Collegium Medicum Uniwerytetu Jagiellońskiego w Krakowie. klinikad@poczta.fm

Przeglad Lekarski
|March 14, 2003
PubMed
Summary

Psoriasis, a common skin disease, is linked to cardiovascular issues. This study explores the connections between psoriasis and conditions like hypertension, lipid disorders, and heart abnormalities.

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Area of Science:

  • Dermatology
  • Immunology
  • Cardiology

Context:

  • Psoriasis affects 2-3% of adults, presenting as a frequent skin disease.
  • It is recognized as a systemic condition with significant immunologic and genetic factors.
  • Microvascular and macrovascular disorders play a crucial role in psoriasis pathogenesis.

Purpose:

  • To present the current scientific understanding of psoriasis pathogenetic mechanisms.
  • To specifically examine the factors linking psoriasis to cardiovascular abnormalities.
  • To review associations between psoriasis and arterial hypertension, lipid and carbohydrate metabolism disorders, and coagulative and heart valve abnormalities.

Summary:

  • Psoriasis pathogenesis involves immunologic and genetic factors, alongside vascular disorders.
  • The study details the etiological, pathological, and epidemiological links between psoriasis and arterial hypertension.
  • It further explores connections to metabolic (lipid, carbohydrate) and hemostatic (coagulative, heart valve) abnormalities.

Impact:

  • Highlights the systemic nature of psoriasis beyond skin manifestations.
  • Emphasizes the critical role of cardiovascular health in psoriasis management.
  • Provides a comprehensive overview for researchers and clinicians on psoriasis comorbidities.

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