[Psoriasis and cardio-vascular disorders]

Psoriasis is one of the most frequent skin diseases. It occurs in adult people with a frequency 2-3%. Psoriasis is a systemic disease with immunologic and genetic determinants. Micro and macro vascular disorders are important for pathogenesis of psoriasis. Authors attempt to show a current scientific statement of pathogenetic mechanisms in psoriasis with special consideration of factors involving cardiovascular abnormalities. In consecutive steps described are associations between psoriasis and arterial hypertension from etiological, pathological and epidemiological point of view. In the same order are reviewed the junctions of psoriasis and lipid and carbohydrate metabolism disorders, as well as coagulative and heart valves abnormalities.