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Related Experiment Video

Updated: Apr 29, 2026

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

Direct stenting.

Emanuele Barbato¹, Jean Marco, William Wijns

¹The Cardiovascular Center, Onze-Lieve Vrouw Ziekenhuis, Aalst, Belgium.

European Heart Journal

|March 14, 2003

Summary

This summary is machine-generated.

Direct stenting, a modern approach to percutaneous coronary interventions, offers improved outcomes and reduced costs. This technique, utilizing advanced stent designs, avoids balloon pre-dilatation, minimizing vessel damage and embolization.

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Area of Science:

Cardiology
Interventional Cardiology
Biomedical Engineering

Background:

Percutaneous coronary interventions (PCI) have been significantly improved by stent technology.
Modern stent designs allow for delivery without pre-dilatation, increasing their use in procedures.

Purpose of the Study:

To evaluate the safety and feasibility of direct stenting compared to conventional balloon-predilatation stenting.
To assess the impact of direct stenting on clinical outcomes, procedural efficiency, and costs.

Main Methods:

Comparison of direct stenting versus balloon-predilatation stenting in selected cases.
Assessment of procedural outcomes, including vessel wall damage, distal embolization, procedure duration, and costs.

Main Results:

Direct stenting demonstrated safety and feasibility, with slightly superior outcomes compared to conventional stenting.
Reduced vessel wall damage and decreased distal embolization were observed with direct stenting.
Significant reductions in procedure costs and duration were achieved.

Conclusions:

Direct stenting is a safe and feasible alternative to conventional stenting in selected PCI cases.
The technique offers benefits in terms of reduced vessel trauma and procedural efficiency.
While not reducing restenosis rates, direct stenting provides economic and clinical advantages.