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Related Experiment Videos

Haematological problems in pregnancy.

Robert F Burrows1

  • 1Maternal-fetal medicine, Monash University, Clayton, Australia. robert.burrows@med.monash.edu.au

Current Opinion in Obstetrics & Gynecology
|March 14, 2003
PubMed
Summary
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Recent reviews on pregnancy hematology highlight a need for more randomized trials. Evidence is growing for managing thrombocytopenia and anemia, but expert opinion still guides much of pregnancy thromboembolic disease treatment.

Area of Science:

  • Obstetrics and Gynecology
  • Hematology
  • Reproductive Medicine

Background:

  • Hematological disorders are frequent causes for obstetric referral.
  • Current management often relies on expert opinion and extrapolation from non-pregnant data.

Purpose of the Study:

  • To review recent publications on hematological issues in pregnancy.
  • To identify areas requiring further research, particularly randomized trials.

Main Methods:

  • Review of recent narrative and randomized controlled trials.
  • Synthesis of evidence on venous thromboembolic disease, thrombocytopenia, and anemia in pregnancy.

Main Results:

  • Guidance exists for venous thromboembolic disease, though lacking randomized trials in pregnant patients.

Related Experiment Videos

  • Consensus is emerging for managing pregnancy-related and idiopathic thrombocytopenic purpura.
  • Randomized trials are evaluating oral iron, intravenous iron, and erythropoietin for non-deficiency anemia.

    • Conclusions:

    • There is a significant need for well-designed randomized trials addressing hematological conditions during pregnancy.
    • High-quality trials are essential to guide the safe and effective use of medications like heparin in pregnancy.