Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mass spectrometry-based proteomics.

Ruedi Aebersold1, Matthias Mann

  • 1Institute for Systems Biology, 1441 North 34th Street, Seattle, Washington 98103-8904, USA. raebersold@systemsbiology.org

Nature
|March 14, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Novel LC System Embeds Analytes in Pre-formed Gradients for Rapid, Ultra-robust Proteomics.

Molecular & cellular proteomics : MCP·2018
Same author

Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2018
Same author

The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications.

Clinical cancer research : an official journal of the American Association for Cancer Research·2018
Same author

In-depth proteomic analyses of <i>Haliotis laevigata</i> (greenlip abalone) nacre and prismatic organic shell matrix.

Proteome science·2018
Same author

Multi-Protein Complexes Studied by Mass Spectrometry.

TheScientificWorldJournal·2018
Same author

In vivo brain GPCR signaling elucidated by phosphoproteomics.

Science (New York, N.Y.)·2018
Same journal

Daily briefing: 'Cyborg' cockroaches breathe underwater with printed suit.

Nature·2026
Same journal

China boosts prestigious grants for young scientists - will it ease competition?

Nature·2026
Same journal

Incoming US science academy chief vows to 'double down' on research.

Nature·2026
Same journal

Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization.

Nature·2026
Same journal

Electrodeposited self-assembled molecules for perovskite photovoltaics.

Nature·2026
Same journal

Neutrino's nursery found: the 'Shadow Blaster'.

Nature·2026
See all related articles

Mass spectrometry-based proteomics is a vital tool in biology and medicine. It enables the identification and quantification of thousands of proteins, advancing molecular, cellular, and systems biology research.

Area of Science:

  • Proteomics
  • Molecular Biology
  • Cellular Biology
  • Systems Biology

Background:

  • Mass spectrometry-based proteomics has emerged as a powerful technology.
  • Its applications span various biological disciplines.

Purpose of the Study:

  • To highlight the indispensable role of mass spectrometry in modern biological research.
  • To showcase its impact on understanding complex biological systems.

Main Methods:

  • Affinity-based isolation techniques for studying protein-protein interactions.
  • Proteome-wide scale analyses.
  • Quantitative mass spectrometry for protein profiling.

Main Results:

  • Successful mapping of organelles.

Related Experiment Videos

  • Concurrent description of the malaria parasite genome and proteome.
  • Generation of quantitative protein profiles across diverse species.

    • Conclusions:

    • Mass spectrometry is crucial for identifying and quantifying thousands of proteins in complex samples.
    • Its capabilities are expected to significantly impact biology and medicine.