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A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
Published on: July 6, 2017
Immunogenetic model
1State Institute for Blood Group Serology, Statens rättskemiska laboratorium, Stockholm 60.
Nature
|October 13, 1972
Different and equally legitimate modes of interpreting serologic reactions will considerably change the image of reality. Some principles of such transformations are briefly outlined and applied to immunogenetic systems.
Different and equally legitimate modes of interpreting serologic reactions will considerably change the image of reality. Some principles of such transformations are briefly outlined and applied to immunogenetic systems.
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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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