[Weather-induced changes in cannabinoid content of hair]

Michael Kury¹, Gisela Skopp, Rainer Mattern

¹Institut für Rechtsmedizin und Verkehrsmedizin, Universität Heidelberg.

Archiv Fur Kriminologie

|March 15, 2003

Abstract:

Authentic hair samples from Cannabis users and a drug free hair sample which was separately spiked with tetrahydrocannabinol (THC), cannabidiol (CBD) or cannabinol (CBN) were exposed outside as well as to natural sunlight at prevailing and elevated humidity in quartz glass tubes during 8 weeks. In addition, authentic and spiked hair samples were exposed to xenon arc radiation in a light exposure cabinet for 24 hours. Stability of THC, CBD and CBN in authentic samples differed from that of the spiked hair. The radiation experiment revealed that CBN could not be measured in hair which had been spiked with THC. Under all conditions chosen the concentrations of THC, CBD and CBN decreased. At high humidity the concentrations declined more rapidly. In both authentic and spiked samples THC was most unstable compared to CBD and CBN. Therefore, in hair analysis determination of CBD and CBN seems promising to detect Cannabis exposure even under unfavorable conditions.

Related Experiment Videos

[Weather-induced changes in cannabinoid content of hair]

Related Concept Videos

Association of prior beta-blocker treatment and outcome in patients with out-of-hospital cardiac arrest.

Step-By-Step Procedure to Identify Previously Unknown Compounds by LC-QTOF-MS Exemplified by an Intoxication With the Methaqualone Analog SL-164.

Single hair analysis for gamma-hydroxybutyric acid-Method optimization, validation, and application.

Storage stability of phosphatidylethanol homologues in whole blood and dried blood spots of nonalcoholics at different temperatures over 60 days.

Monitoring of phosphatidylethanol in dried blood spots and of ethyl glucuronide in hair over 6 months of alcohol consumption.

Formation of phosphatidylethanol and ethylglucuronide after low to moderate alcohol consumption in volunteers with a previous three-week alcohol abstinence.

Subnuclear lipid-containing vacuolization in cases of ketoacidosis - correlation of morphological findings and ketone body concentrations.

So-called skin signs in acute pancreatitis.

Interrupted (self -)medication with pancuronium(bromide) and fatal outcome.

The Clinical-Forensic Network of Styria as a pilot project: findings of the accompanying socio-scientific study.

Justus v. Liebig and forensic toxicology.

About the influence of burial on the development of forensically relevant blow fly larvae.

Accuracy of angioboost software versus routine angiography for assessing the degree of coronary artery lesion occlusion.

Analysis of characteristic flavor compounds in coffee peels subjected to different thermal processing treatments based on GC-IMS and HS-SPME-GC-MS combined with chemical pattern recognition.

Analytical validation and clinical performance of a chemiluminescence immunoassay panel for plasma biomarkers in Alzheimer's disease: a preliminary study.

Colorimetric-catalytic-fluorescence triple-mode lateral flow immunoassay based on Au@PtPd NPs for sensitive detection of capsaicinoids: Evaluation of edible oil and chili quality.

A frozen-suspension external calibration strategy for quantitative imaging of Ce in fresh animal soft tissues by CLA-ICP-MS.

FOCUS-ischemia: A real-world comparison of an ischemia-focused analytical strategy and conventional multiparametric stress CMR.

Related Experiment Videos

[Weather-induced changes in cannabinoid content of hair]

Abstract:

Related Concept Videos

Related Articles