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Corneal neovascularization possibly associated with latanoprost therapy
M Orhan1, H Kerimoğlu, M Irkeç
1Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey. morhan@hacettepe.edu.tr
Purpose:
To report a case of corneal neovascularization possibly associated with latanoprost therapy.
Case Report:
A 67-year-old man developed a progressive stromal corneal neovascularization in his right eye within eight months of a corneal trauma. At admission, he was receiving latanoprost 0.005% therapy. His topical medications were rearranged: latanoprost was replaced with carteolol hydrochloride 1% twice daily bilaterally and prednisolone acetate 1% was added twice daily in the right eye.
Results:
One month later, he presented regression of the corneal neovascularization and an increase in visual acuity.
Conclusions:
Latanoprost, an arachidonic acid derivative, could have directly or indirectly stimulated the corneal neovascularization in this patient with a history of nonpenetrating corneal trauma.