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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
[Effect of cardiac rehabilitation on left ventricular function and exertion capacity in patients with chronic
Artur Klecha1, Bogumiła Bacior, Aleksandra Kubinyi
1I Klinika Kardiologii, Instytut Kardiologii Collegium Medicum Uniwersytet Jagielloński, 31-501 Kraków, ul. Kopernika 17.
Insights
Physical rehabilitation significantly improves exercise capacity in patients with congestive heart failure (CHF). This 6-month study found trained CHF patients showed marked gains in exercise time, workload, and VO2 peak, while the untrained group saw no change.
Area of Science:
- Cardiology
- Exercise Physiology
- Medical Imaging
Background:
- Congestive heart failure (CHF) management often includes cardiac rehabilitation.
- The impact of physical rehabilitation on left ventricular (LV) structure and function in CHF patients remains debated.
- Cardiac magnetic resonance (CMR) offers precise, noninvasive assessment of cardiac parameters.
Purpose of the Study:
- To evaluate the effects of a 6-month physical rehabilitation program on exercise capacity and LV morphology in CHF patients (NYHA class II-III, LVEF < 35%).
- To compare changes between a trained group and a control group using CMR and cardiopulmonary exercise testing.
Main Methods:
- 16 CHF patients were randomized into a trained group (progressive workload) or a control group (no training).
- Both groups underwent baseline and 6-month CMR and cardiopulmonary exercise tests.
- Groups were matched for age, gender, and NYHA class.
Main Results:
- The trained group demonstrated significant improvements in exercise time, maximal workload, and peak oxygen consumption (VO2 peak) (p < 0.05).
- No significant changes in exercise capacity were observed in the untrained control group.
- No significant differences in morphological LV parameters were found between groups at baseline or follow-up.
Conclusions:
- Six months of progressive physical rehabilitation significantly enhances exercise capacity in CHF patients.
- Physical rehabilitation does not appear to alter LV morphological parameters in this CHF cohort.
- Exercise capacity improvements in CHF patients are achievable through structured training programs.
Unlabelled:
Cardiac rehabilitation is proven to be an effective method of treatment in congestive heart failure (CHF) and it has a positive influence on exercise capacity. There are controversies concerning the influence of physical rehabilitation on morphological and functional parameters of the left ventricle. Cardiac magnetic resonance (CMR) is a very precise noninvasive method of cardiac examination. The aim of this study was to assess changes in exercise capacity and in morphological parameters of the left ventricle in patients with CHF (NYHA class II and III, ejection fraction less than 35%) undergoing 6-months of physical rehabilitation. 16 patients were divided into two groups: A (7 pts) trained with progressive workload and group B (9 pts) did not trained. Groups were not different in terms of age, gender and NYHA class. In all patients, CMR and cardiopulmonary exercise test were performed at baseline and after 6 months.
Results:
At baseline, both groups were similar with respect to the LV dimensions, thickness of LV walls and exercise capacity. At follow up, we observed an increase in exercise capacity in only the trained group (A). Exercise time increased from 357.1 +/- 30 sec. to 830.1 +/- 59 sec. (p < 0.05); max. workload from 2.7 +/- 0.36 MET to 6.21 +/- 0.8 MET (p < 0.05) and VO2 peak from 14.3 +/- 1.8 ml/kg/min to 18.8 +/- 2.1 ml/kg/min (p < 0.05). In group B (not trained) there were no changes after 6 months in these parameters. Morphological LV parameters were similar in both groups at baseline and after 6-months of rehabilitation.
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