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Basal cell and squamous cell carcinoma.
1Department of Dermatology, Oregon Health & Science University, 3181 SW Sam Jackson Dr, Portland, OR 97201-3098, USA.
Seminars in Oncology Nursing
|March 18, 2003
Summary
Basal cell and squamous cell carcinoma are common skin cancers, with over a million US cases annually. Early detection and treatment are key to high curability, with recent advances in understanding skin carcinogenesis.
Area of Science:
- Dermatology
- Oncology
- Molecular Biology
Background:
- Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most common types of skin cancer.
- These keratinocyte cancers affect over one million individuals annually in the United States.
- Understanding the molecular basis of sunlight-induced carcinogenesis is crucial for prevention and treatment.
Purpose of the Study:
- To provide a comprehensive overview of BCC and SCC.
- To describe their clinical and histologic subtypes, pathophysiology, and recognition.
- To outline current and emerging treatment options and discuss the molecular biology of skin cancer.
Main Methods:
- Literature review encompassing journal and review articles.
- Inclusion of research studies and textbooks.
- Synthesis of clinical practice guidelines and expert consensus.
Main Results:
- BCC and SCC are highly curable when diagnosed and treated early.
- Significant advancements have been made in understanding the molecular mechanisms of skin carcinogenesis over the past decade.
- Newer management and treatment strategies for these keratinocyte cancers are emerging.
Conclusions:
- Early detection and prompt treatment are critical for favorable outcomes in BCC and SCC.
- Ongoing research continues to refine our understanding of skin cancer development.
- Nurses play a vital role in identifying suspicious lesions and facilitating timely patient referrals, thereby reducing morbidity and mortality.