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DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
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DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

Published on: March 15, 2011

The potential of DNA microarrays for the care of children

Michael D Bates1

  • 1Division of Gastroenterology, Hepatology, and Nutrition, and the Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA. michael.bates@cchmc.org

The Journal of Pediatrics
|March 18, 2003
PubMed
Abstract

No abstract available in PubMed .

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DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...