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Temporary amniotic membrane patching for acute chemical burns.

A Kobayashi1, Y Shirao, T Yoshita

  • 1Department of Ophthamology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan. kobaya@kenroku.kanazawa-u.ac.jp

Eye (London, England)
|March 18, 2003
PubMed
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Temporary amniotic membrane patching (AMP) offers a useful surgical technique for acute ocular chemical injuries. This method aids in rapid healing and pain reduction, preserving ocular surface integrity.

Area of Science:

  • Ophthalmology
  • Regenerative Medicine
  • Trauma Surgery

Background:

  • Acute ocular chemical injuries often result in severe corneal and conjunctival epithelial defects.
  • Prompt management is crucial to prevent long-term visual impairment and ocular surface complications.

Observation:

  • A modified temporary amniotic membrane patching (AMP) technique was applied to five patients with moderate to severe acute chemical eye injuries (Roper-Hall grade II-III).
  • Diverse chemical agents including acids and alkalis caused the injuries.
  • Patients experienced significant pain relief post-procedure.

Findings:

  • All patients demonstrated rapid corneal epithelialization and improved visual acuity within two weeks of AMP removal.
  • The ocular surface remained stable with no cicatricial complications during a mean follow-up of 19.6 months.

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Implications:

  • Immediate AMP is a valuable therapeutic option for moderately severe acute ocular chemical injuries.
  • This surgical approach promotes rapid healing, alleviates pain, and maintains ocular surface integrity.