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[A clinical and histological study of Bio-Oss in combination with guided bone regeneration membrane technique]
1Center of Implantation, Peking University School of Stomatology, Beijing 100081, China.
Objective:
To evaluate the reliability of Bio-Oss particles as bone grafts in combination with membrane-technique.
Methods:
6 small biopsy specimens were retrieved without causing iatrogenic damage in 6 patients (implant sites). The Donath's hard tissue section and micro grinding technique was adopted, and Leval Laczko staining method was used.
Results:
The histological results showed Bio-Oss particles were easily distinguished from the newly formed bone, but new bone was formed among different particles of Bio-Oss, no connective tissue was found. Intimate contact between newly formed bone and particles of the graft was present.
Conclusions:
Bio-Oss appears to be highly biocompatible and osteoconductive. It can be used success fully as a bone substitute in combination with guided bone regeneration membrane technique.