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Coeliac disease and autoimmune cholangitis: a case report
M Marignani1, S Angeletti, T Mari
1Department of Hepatogastroenterology, S. Giacomo Hospital, Rome, Italy. mmarignani@hotmail.com
Summary
Autoimmune cholangitis can co-occur with other autoimmune conditions. This case highlights a rare link between autoimmune cholangitis and celiac disease, where treating celiac disease reversed severe anemia.
Area of Science:
- Gastroenterology
- Immunology
- Hematology
Background:
- Autoimmune cholangitis is frequently associated with other autoimmune disorders.
- Microcytic anemia is a common complication of various systemic diseases.
Observation:
- A 58-year-old female presented with severe microcytic anemia refractory to oral iron therapy.
- This patient had a history suggestive of autoimmune cholangitis.
Findings:
- Diagnostic workup revealed coeliac disease, an uncommon comorbidity with autoimmune cholangitis.
- Initiation of a gluten-free diet and hematinic treatment resulted in complete resolution of the anemia.
Implications:
- This case underscores the importance of considering celiac disease in patients with autoimmune cholangitis and unexplained anemia.
- Early diagnosis and management of celiac disease can effectively treat associated anemia.
- Highlights the complex interplay between autoimmune conditions and their gastrointestinal manifestations.