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Updated: Aug 8, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
Activated recombinant factor VII for control of diffuse bleeding after implantation of ventricular assist device
Evgenij V Potapov1, Miralem Pasic, Matthias Bauer
1Deutsches Herzzentrum Berlin, Berlin, Germany. potapov@dhzb.de
Abstract:
Patients with prolonged severe cardiogenic shock requiring implantation of a biventricular assist device may develop diffuse bleeding due to alteration of hepatic and renal function and subsequent coagulopathy. Bleeding control in these patients may be difficult despite massive use of blood products. We report on the successful use of recombinant activated factor VII for control of massive bleeding after implantation of a biventricular assist device in a patient with prolonged severe cardiogenic shock.
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